Elevation of Serum Soluble E- and P-Selectin in Patients with Hypertension Is Reversed by Benidipine, a Long-Acting Calcium Channel Blocker
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چکیده
منابع مشابه
Soluble E-selectin and P-Selectin Serum Levels in Patients with Psoriasis Compared to Healthy Controls
Introduction: Psoriasis is an inflammatory skin disease in which abnormal individual immune reactivity plays an important role. Eselectin and P-selectin are adhesion molecules expressed on vascular endothelial cells in several inflammatory skin diseases, including psoriasis. The aim of the present study was to describe selected immunological changes, concerning adhesion molecules status (sEsele...
متن کاملBenidipine, a long-acting calcium channel blocker, inhibits cardiac remodeling in pressure-overloaded mice.
OBJECTIVE The effects of long-acting calcium channel blockers (CCBs) on pressure overload-induced cardiac remodeling are seldom studied in animals. We evaluated the effects of benidipine, a long-acting CCB, on cardiac remodeling. METHODS Rat neonatal cardiac myocytes were used to examine the influence of benidipine on protein synthesis. Cardiac remodeling was induced in C57 B6/J mice by trans...
متن کاملLevels of Serum Soluble P-Selectin and E-Selectin in Psoriatıc Patients
Vol. 26 No. 2, 2014 275 Received January 3, 2013, Revised April 6, 2013, Accepted for publication May 14, 2013 *Recep Kesli is now with Department of Microbiology, Afyon University Faculty of Medicine, Afyonkarahisar, Turkey. Corresponding author: Arzu Ataseven, Department of Dermatology, Konya Training and Research Hospital, Meram, Konya 42090, Turkey. Tel: 90-0 505 691 58 59, Fax: 90-0 332 32...
متن کاملEvaluation of Mutagenicity of Mebudipine, a New Calcium Channel Blocker
Mebudipine is a new dihydropyridine calcium channel blocker, synthesized in our laboratory, for treatment of hypertension. It has shown a better efficacy than other drugs in this group. For assessing the risks of this drug, certain safety tests in the preclinical stage have been performed. In this study mutagenic effect of mebudipine was evaluated using Ames assay that could assess the mutageni...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2005
ISSN: 0916-9636,1348-4214
DOI: 10.1291/hypres.28.871